India A were 308-4 at stumps on day three of the first four-day match in Bloemfontein, still 201 runs behind South Africa A.
Abhimanyu Easwaran top-scored for the visitors with 103 after captain Priyank Panchal had made 96.
Lutho Sipamla (2-73) and George Linde (2-32) were SA A’s most successful bowlers.
Linde trapped Panchal lbw to end a 142-second-wicket partnership and then had Hanuma Vihari caught behind by Sinethemba Qeshile for 25.
George Linde picked up the second wicket for SA 'A' shortly after lunch on day 3.
He removed Priyank Panchal just 4 runs short of a century when he trapped him LBW after missing an attempted sweep shot.#SAAvINDA pic.twitter.com/NEpEoIcQJs
— Shaun (@Shaun_Analytics) November 25, 2021
Easwaran was caught by Sarel Erwee off the bowling of Sipamla with the total on 294.
Baba Aparajith (19*) and Upendra Yadav (5*) were still at the crease when bad light stopped play.